Nine biomarkers.
One powerful age score.
PhenoAge combines 9 clinical biomarkers found to strongly correlate with aging and mortality into a single, validated biological age score.
Albumin
Liver function and nutrition status. Low levels are associated with increased mortality risk.
Creatinine
Kidney filtration capacity. Reflects how well your kidneys are clearing waste from the blood.
Glucose
Metabolic health and insulin sensitivity. Elevated levels accelerate biological aging.
C-Reactive Protein (CRP)
Systemic inflammation marker. Chronic inflammation is a key driver of accelerated aging.
Lymphocyte Percentage
Immune system strength. Declining lymphocyte counts signal immune system aging.
Mean Cell Volume (MCV)
Red blood cell health. Abnormal cell size indicates nutritional deficiencies or blood disorders.
Red Cell Distribution Width (RDW)
Cellular aging variation. Higher variability in red blood cell size is linked to faster aging.
Alkaline Phosphatase
Liver and bone metabolism. Elevated levels may indicate liver stress or bone turnover issues.
White Blood Cell Count
Immune response activity. Elevated counts can indicate chronic inflammation or infection.
From blood test to biological age
in three steps
Get a Blood Test
Visit any Quest Diagnostics location or use your recent blood work. Standard CBC, CMP, and CRP panels are all that's needed.
We Calculate Your Age
Our algorithm applies Dr. Levine's validated PhenoAge formula to your 9 biomarkers, computing your precise biological age.
Get Your Report
Receive your biological age score, biomarker breakdown, personalized recommendations, and optional consultation.
Already have blood test results?
Upload them directly at our PhenoAge Analysis page for instant results. No waiting, no additional lab visits needed.
Upload Blood Test Results
Everything you need to
understand your aging
Lab Blood Test
Administered by Quest Diagnostics (US) or select UK locations. Standard panels that capture all 9 PhenoAge biomarkers.
- CBC with differential
- Comprehensive Metabolic Panel
- High-sensitivity CRP
Biological Age Report
A comprehensive analysis of your biological age with actionable insights for health optimization.
- Your PhenoAge score
- Individual biomarker analysis
- Age-matched population comparison
- Personalized health recommendations
Follow-up Analysis
With a second test, track how your interventions are impacting your biological age over time.
- Before and after comparison
- Treatment impact measurement
- Lifestyle change assessment
Developed by leading
aging researchers
PhenoAge was developed in 2018 by Dr. Morgan Levine, Dr. Luigi Ferrucci (National Institute on Aging), and Dr. Steve Horvath (UCLA). Published in the journal Aging, the study analyzed data from over 9,000 individuals in NHANES III.
The algorithm identifies patterns in 9 standard blood biomarkers that together create a composite measure of biological aging. Unlike your birth date, this score reflects your actual physiological state and can be improved through lifestyle interventions.
PhenoAge was found to predict all-cause mortality, cancer, healthspan, physical functioning, and Alzheimer's disease risk—making it one of the most comprehensive blood-based aging biomarkers available.
"An Epigenetic Biomarker of Aging for Lifespan and Healthspan"
PhenoAge was found to predict all-cause mortality, cancer, healthspan, physical functioning, and Alzheimer's disease risk—outperforming previous blood-based age estimators across all measured outcomes.
Which test is
right for you?
Both PhenoAge and GrimAge measure biological age, but they use different approaches. Here's how they compare.
| Feature | PhenoAge | GrimAge |
|---|---|---|
| Sample Type | Blood draw at lab | At-home blood collection kit |
| What It Measures | 9 clinical biomarkers | DNA methylation patterns |
| Results Timeline | Days | 4-6 weeks |
| Best For | Quick baseline, regular monitoring | Deep epigenetic insights, mortality prediction |
| Price Range | $ Affordable | $$$ Comprehensive |
| Actionable Components | 9 biomarkers | 7 risk factor systems |
Want the deepest insights into your epigenetic age?
Explore GrimAge Testing
Know your biological age
in days, not weeks
A simple blood test reveals how fast you're aging—and what you can do about it.
Private & Secure • Results in Days • Peer-Reviewed Science
Common questions
Everything you need to know about PhenoAge and biological age testing from a blood sample.
What is biological age?
What is PhenoAge?
What blood tests do I need?
How quickly do I get results?
How is PhenoAge different from GrimAge?
Can I use blood work I already have?
Where can I get tested?
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to screen, diagnose, treat, cure, or prevent any disease or condition.