Stay up-to-date on latest anti-aging research from top longevity scientists.

Aging Research Tests & Tools Used by Top Researchers

Your Gateway to Precision Longevity

About powered by Clock Foundation is the direct-to-consumer and clinical side of the Clock Foundation, a longevity research-oriented, non-profit based in Los Angeles. The Clock Foundation was founded by Steve Horvath and Bobby Brooke.

Our mission is to enable everyone to achieve longer, healthier live using safe and affordable interventions.

In the short term, we aim to reduce cost of epigenetic age testing, develop increasingly powerful biomarkers for predicting healthspan and lifespan, and provide a comprehensive platform of tools and testing services for longevity researchers, clinics and individuals.

Why? Measure. Evaluate. Improve.

Measure Top Longevity Biomarkers

Age is the strongest risk factor for mortality and disease, including disease, dementia, and COVID-19.

  • Biological age measurements (like GrimAge) are built to represent your actual age risk and have been shown to be more accurate than chronological age alone.
  • Fortunately, your biological age is modifiable, meaning you can change it.

Evaluate Changes

Tracking can help you see changes over time and decide whether those changes are having an anti-aging impact.  

  • Understand the impact diet and lifestyles changes like exercise have on your rate of aging.
  • Monitor if advanced anti-aging treatments are having on your rate of aging.
  • Use software we have to keep organized, which helps convert health data into knowledge

Publish Results Together

We believe that developing longevity medicine that improves human healthspan and lifespan will take a highly engaged community of physicians, scientists, health coaches, treatment developers, as well as patients and clinical trial volunteers.  

  • Participate in one of several community-led trials focused on different anti-aging protocols.
  • Share data and insights from your journey into living longer, heathier lives.

Tools for Doctors, Researchers and Patients

Features of our Web Portal: Test Management, Reports and Clinical Trial Support

Biological Age Tests: Order, Manage, Schedule

🛒 Whether individual or in bulk, our web portal makes it easy to order our biological age tests at our best prices. 

📦 Download lab forms and track shipments and logistics.

👥 Manage patients, assign and register samples/kits, and track processing. 

Track, Analyze and Improve Age

📝 View and download individual test results, reports, and raw data. 

📊 Access longitudinal reports, compare epigenetic clocks and view advanced treatment analysis. 

🎯 Track patients and cohorts over time using tools used by academics, researchers and clinics. 


Advanced Features

Our portal and software is built for longevity programs and clinical trials and has been used on clinical trials, clinical practices, commercial projects, and academic studies.

Trial Participant / Patient Portal

  • Manage Recruitment, Screening, Enrollment and Onboarding.
  • Personalized treatment tracker.
  • Provide patient access to biological test results and program updates.
  • Assign schedule of events, testing points, and surveys including daily periodic health questionaires.

Most Cited Biological Age Tests used globally.

Don’t trust “black box” age tests! Steve Horvath’s GrimAge Test was developed by a international team of researchers and is the most cited longevity test currently available with over 1000 citations and references on Google Scholar. 

Beware of tests in nonstandard proprietary data formats! With all of our tests, you get access to your RAW data including DNA methylation data. Enabling you to not only control your health data but enables you to compare and utilized future algorithms and health services. 

You can depend on the “gold standard” tests used by top longevity researchers around the world. 

How We Measure Aging

Biological Aging Tests Developed & Used by Top Longevity Researchers

Blood Testing (PhenoAge)

Close up of hand of laboratory technician holding test tube with blood sample with another test tubes in backside on white background.
  • The PhenoAge Test is blood plasma biological age test.
  • Based on levels of 9 clinical biomarkers circulating in blood, PhenoAge has been found to strongly correlate with onset of age-related diseases and mortality.
  • Requires a simple lab-based blood test.

Epigenetic Age Testing (GrimAge)

  • GrimAge is an epigenetic age test based on DNA methylation that predict your biological age and mortality risk.
  • Developed in the Horvath lab at UCLA and validated across a wide variety of human cell types and tissues.
  • Validated as most accurate mortality predictor and provides personalized age risk factors and anti-aging recommendations.

3rd Generation Epigenetic Clock

Universal Horvath - Basic v1 - alt 1 - no text
  • Universal Horvath Test is the World's Only Third Generation* epigenetic clock test.
  • Developed using data from over 180 mammalian species and baesd on the most conserved epigenetic age markers shared across animals, this test reveals universal age and your pan-mammalian rate of DNA aging.
  • 🔗 Published in Nature Aging in 2023.
  • Available by request only.

Why Should I Track My Patient's Biological Age?

Make Better Choices. Improved ROIs

Identify premature aging in your patients.
We all age in different ways. By tracking biological age, you can proactively understand how a patient is aging and proactively take steps to prevent pre-mature aging and early death.

Evaluate impact of diet, exercise, and lifestyle.
Many factors impact aging. We can quantify the longevity impact of diet, exercise, medicine and even supplements so you can make better recommendations and navigate best choices for health and longevity.

Run Targeted Anti-Aging Programs, Studies and Trials
Whether it’s a formal clinical trial, early case study or longevity program, our custom software portal and cutting-edge biological age testing options and analysis can help you succeed. 

Better care at any age.
Anyone can benefit from having their biological age measured, regardless of how old they are. Whether someone is in their 70s or in their 30s, knowing one’s “true” biological age and if someone has accelerated pace aging can help you decide and implement positive lifestyle changes or other anti-aging intervention changes to start making a difference nowwith how quickly they age.

Contribute to longevity research (for humans and pets)!

Recent Media Coverage & Interviews

National Geographic: Can aging be cured? Scientists are giving it a try

The Guardian: Real age versus biological age

Financial Times: Can we defeat death?

Bloomberg: Will Humans Live to 150? Science Is Working on It

Quanta Magazine: Epigenetic ‘Clocks’ Predict Animals’ True Biological Age

For Clinics, Doctors and Coaches

Measure Biological Aging. Improve Patient Care and Outcomes.

Doctor / Clinic Signup

  • Our Clinical Users can access age test options for the most advanced at-home or at-the-clinic biological age testing.
  • Our easy to navigate clinical portal makes it seamless to manage patients, buy or schedule your testing, track kits and samples, view results and view the statistical analysis for an individual patient or cohort.
  • ADVANCED: Want to run a clinical trial or longevity program, contact us to see how we can provide a trial manager and patient experience for onboarding, enrollment, treatment updates, and surveys!

View Demo of Clinical Portal

CF Kit 3-GrayBG
  • Want to learn more biological age testing and our products and service?
  • Curious how this will work with your existing practice and processes?
  • Check out our demo!

Frequently Asked Questions

What is biological age? What is a biological age test?

Biological age refers to your age on a biological level compared to your chronological age or how many birthdays have passed for you. 

Biological age tests look at changes in your biology that are indicative of biological aging. In our case, our biological age test uses what is called an epigenetic clock to calculate your biological age.  

Fortunately, your biological age is modifiable, meaning you can change it. Tracking your biological age can help you see changes over time and understand the impact diet, lifestyles changes, and anti-aging treatments are having on your rate of aging.

How does it work?

After ordering, you’ll receive different instructions depending on which test you’ve obtained, or which program you’ve entered.  In each case by email we’ll detail how the test works and the steps ahead necessary for collection.

For everyone obtaining testing, this initial email will include:

  1. A link to an online survey to register your test kit and to complete a brief intake questionnaire;
  2. For the PhenoAge test in the U.S., a form that enables you to obtain your blood draw, along with instructions on how to schedule an appointment; and
  3. For the GrimAge epigenetic age test, instructions on how to collect and return your at-home blood collection kit.

You will receive your initial test report and results as soon as each of the above steps have been completed.  For the PhenoAge blood test, this is typically within 1-2 weeks after your blood draw.  For the Grimage epigenetic clock test, the typical turnaround time is 3-4 weeks after return of your sample. 

Once you receive your initial results, you’ll also be able to book a 1-on-1 consultation with our team to discuss.

Each month you’ll also receive separate notifications about our community events, where we discuss new treatments and longevity strategies.

What is epigenetics?

Epigenetics is the study of how genes are turned off and on during an animal’s lifetime, including humans. 

A Greek word meaning “above genetics”, epigenetics is the study of changes in gene function that occur without detectable changes to DNA sequence. What this means is that your gene expression (like what proteins your cells produce) changes but your gene sequences themselves do not change. 

Epigenetics most often involves changes that affect gene activity and expression. These epigenetic changes can occur due to normal biological development but they can also result from external or environmental factors like food choices, stress levels or even injury.

How is this test different from a DNA test like 23andMe?

A genetic or DNA test looks at what your DNA contains whereas an epigenetic age test measures various epigenetic changes on our DNA itself. Unlike DNA, your epigenetics are modifiable.

Many cells in the body have an “epigenetic clock” that keeps track of how quickly they are aging or, more accurately, how much damage has been done since they were created.

Our test provides your biological age as well as various key drivers of your aging.

What is the science behind these tests, including GrimAge?

DNA methylation is a process where methyl groups are added to DNA to influence gene expression, and which are critical for normal human development, defining cell identity, as well as for rejuvenation and reprogramming.  Highly accurate estimators of chronological age have been developed are known as epigenetic aging clocks, which can predict chronological age through development and across the lifespan (Horvath 2013, Horvath & Raj 2018). 

Increasingly these clocks are also being used as a measure of biological age as certain measures – most notably GrimAge (Lu 2019, Li 2020), which is able to predict future morbidity and mortality risk.  GrimAge also performs well for predicting functional decline and onset of major age-related diseases, including heart disease, cancer onset, multi-modal measures of brain health, kidney disease, fatty liver, respiratory function, and more (Lu 2019, Hillary 2018, Hillary 2020, McCrory 2020). These peer reviewed and independent studies have also shown that it performs reliably across large diverse populations.  

Many researchers conclude today that overall epigenetic clocks now represent the most robust measure of biological age (Li 2020, Jylhava et al 2017, Justice & Kritchevsky 2020).

Where do you ship? Do you ship internationally?

We currently ship to the United States, UK and Europe and serviced by labs in Los Angeles, USA, and Manchester, UK.

Please contact us if you are located elsewhere and are still interested in purchasing a test or participating in an anti-aging trial.


These statements have not been evaluated by the Food and Drug Administration. These products are not intended to screen, diagnose, treat, cure, or prevent any disease or condition or assess risk of any disease or condition. Unless advised by your healthcare professional, biological age should not be used to determine or alter any age-related health or medical treatments based on your chronological age.

Let’s Stay In Touch


© 2023 Clock Foundation.

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