Gold Standard Epigenetic Clock

The Most Validated
Predictor of
Biological Aging

GrimAge uses DNA methylation to reveal your true biological age and predict health trajectory. Developed by Dr. Steve Horvath at UCLA, it's the only clock that directly predicts time-to-death and disease onset.

Order Your Kit See the Science
IRB-Ready
At-Home Testing
Ships US, UK & EU
Biological Age 42
Chrono: 48 -6 YEARS
YOUNGER
OLDER
Health Score
92/100
Age Acceleration
-0.8 yrs/yr
The Science

Your DNA tells a story.
GrimAge reads it.

Unlike your genetic code which is fixed at birth, your epigenome changes over time. DNA methylation—chemical markers on your DNA—accumulate patterns that reflect your true biological age. Think of your genome as the blueprint and your epigenome as the notes written in the margins over a lifetime.

GrimAge analyzes specific methylation patterns to calculate your biological age with remarkable accuracy. Developed by Dr. Steve Horvath at UCLA, it's the only clock that directly predicts time-to-death and disease onset.

The test breaks down your results into 7 actionable components—showing exactly which factors are aging you faster and where you can intervene.

Peer-reviewed research
Validated in 14+ cohorts

Your GrimAge Report Includes:

Overall Biological Age
Your true cellular age vs chronological
Age Acceleration Score
Are you aging faster or slower than normal?
7 Risk Factor Components
ADM, B2M, Cystatin C, GDF15, Leptin, PAI1, TIMP1
Personalized Recommendations
Evidence-based interventions for your results
1-on-1 Consultation
Expert review of your results & next steps
Simple Process

From order to insights in 4 steps

1
Order Online

Choose your package and receive a collection kit at your door.

2
Register & Health Survey

Complete your profile and a brief health questionnaire to personalize your report.

3
Collect Sample

Simple at-home blood collection kit. Takes approximately 5 minutes.

4
Get Results

Receive your report in approximately 4–6 weeks, including a 1-on-1 consultation.

Everything You Need

What's included with your test

At-Home Blood Collection Kit

  • Simple at-home testing
  • Takes approximately 5 minutes
  • Express mail return included

Advanced Healthy Age Report

  • GrimAge biological age score
  • Epigenetic aging risk factors
  • Anti-aging recommendations
  • Raw DNA methylation data upon request

Longevity 1:1 Consultation

  • Expert discussion of results
  • Personalized recommendations
  • Actionable next steps for longevity
Rigorous Science

The most validated aging biomarker in existence

GrimAge isn't just another test—it's backed by an unprecedented body of peer-reviewed research and independent validation.

750+
Scientific Citations
100+
Collaborating Scientists
14+
Independent Validation Cohorts
2019
Original Publication
Landmark Paper

"DNA methylation GrimAge strongly predicts lifespan and healthspan"

The original GrimAge paper demonstrated that a 7.5-year acceleration in GrimAge equals a doubling of mortality risk. Conversely, a 7.5-year reduction means approximately 50% lower mortality risk.

Lu, Quach, Wilson, et al. • Aging (Albany NY), 2019
Editor's Choice

"GrimAge Outperforms Other Epigenetic Clocks in Prediction of Mortality"

Independent validation by Trinity College Dublin confirmed GrimAge as the most accurate epigenetic predictor of age-related clinical phenotypes and all-cause mortality.

McCrory, Fiorito, et al. • Journals of Gerontology, 2021
Used by Researchers from
Harvard UCLA Stanford Yale Duke Cambridge Mass General Brigham Broad Institute
Clinical Validation

Validated for Major Age-Related Conditions

GrimAge has been shown to predict risk across the full spectrum of aging-related diseases.

Cardiovascular Disease
Cancer Risk
Cognitive Decline
Diabetes Risk
Respiratory Function
Immune System Aging
Kidney Function
Frailty & Mortality
Why GrimAge?

Not all age tests are created equal

There are many biological age tests on the market. Here's why GrimAge stands above the rest.

Feature GrimAge Other Clocks DNA Tests (23andMe)
Predicts mortality risk
Measures epigenetic changes
Shows modifiable factors
Responds to interventions
Validated in clinical studies 14+ cohorts Varies N/A
Actionable health insights

Ready to discover your
biological age?

Get the gold-standard epigenetic test that predicts your health trajectory with unmatched accuracy.

Order GrimAge Test Upload Existing Data

Already have IDAT methylation data? Upload it for free analysis on our epigenetic data page.

FAQ

Common questions

Everything you need to know about GrimAge epigenetic testing and what to expect.

What is biological age?
Biological age is your age on a cellular level compared to chronological age. Unlike your birth date, biological age is modifiable. Tracking it helps measure the impact of diet, lifestyle, and treatments on your aging.
How is GrimAge different from other epigenetic clocks?
GrimAge is a second-generation clock that directly predicts mortality and disease onset. It outperforms Horvath's original clock, Hannum's clock, and PhenoAge in mortality prediction. It's considered the gold standard in longevity research.
What is the difference between PhenoAge and GrimAge?
PhenoAge uses 9 clinical biomarkers from a blood test, with results available in days. GrimAge uses DNA methylation from an at-home blood collection kit, with results in 4–6 weeks. GrimAge offers deeper epigenetic insights and personalized aging drivers.
How does testing work?
Order online, receive a welcome email with instructions, complete a health survey, collect your at-home blood sample (approximately 5 minutes), ship it back with the prepaid label, receive your results in 4–6 weeks, and book your 1-on-1 consultation.
How is this different from 23andMe?
23andMe looks at your fixed genetic code—the DNA sequence you were born with that never changes. An epigenetic test measures changes on your DNA—DNA methylation patterns that change over time based on diet, exercise, stress, and environment. Unlike your DNA sequence, epigenetics are modifiable.
Where do you ship?
We ship to the United States, United Kingdom, and European Union. US samples are processed in Los Angeles, while UK and EU samples are processed in Manchester. All kits include prepaid return shipping.
Can I use data from another provider?
Yes! If you already have IDAT methylation data from TruDiagnostic, Elysium, or any Illumina array provider, you can upload it for free GrimAge analysis at our epigenetic data page.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to screen, diagnose, treat, cure, or prevent any disease or condition.